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The rebirth of iPSCs: Towards a healthier epigenetic landscape
It is well recognized that transcription factor-induced iPSCs carry an aberrant genetic and epigenetic makeup. However, it is not clear whether these defects are developed de novo due to the reprogramming process or inherited from the somatic source cells. Ma and colleagues presented convincing data...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Chongqing Medical University
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146140/ https://www.ncbi.nlm.nih.gov/pubmed/30258858 http://dx.doi.org/10.1016/j.gendis.2014.08.002 |