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Clonal hematopoiesis of indeterminate potential (CHIP): A potential contributor to atherlosclerotic cardio/cerebro-vascular diseases?

At least 10% of the elderly population above the age of 70 carry a condition termed clonal hematopoiesis indeterminate potential (CHIP) due to oligoclonal expansion of mutated hematopoietic stem cells. Although CHIP is known to predispose patients to a higher risk of malignant blood disorders, the r...

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Detalles Bibliográficos
Autores principales: Li, Fei, Wu, Xiaojing, Zhou, Qi, Zhu, Dennis Weixi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146228/
https://www.ncbi.nlm.nih.gov/pubmed/30258936
http://dx.doi.org/10.1016/j.gendis.2018.04.001