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Identification of a novel c-Myc inhibitor with antitumor effects on multiple myeloma cells

Increasing evidence shows that c-Myc oncoprotein is tightly associated with multiple myeloma (MM) progression. Herein, we identified compound 7594-0035, which is a novel inhibitor that specifically targets c-Myc. It was identified from the ChemDiv compound database by molecular docking-based, high-t...

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Detalles Bibliográficos
Autores principales: Yao, Ruosi, Sun, Xiaoyang, Xie, Yu, Sun, Xiaoshen, Yao, Yao, Li, Hujun, Li, Zhenyu, Gao, Jian, Xu, Kailin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146296/
https://www.ncbi.nlm.nih.gov/pubmed/30068698
http://dx.doi.org/10.1042/BSR20181027