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Hypoxia-induced alterations in the lung ubiquitin proteasome system during pulmonary hypertension pathogenesis

Pulmonary hypertension (PH) is a clinical disorder characterized by sustained increases in pulmonary vascular resistance and pressure that can lead to right ventricular (RV) hypertrophy and ultimately RV failure and death. The molecular pathogenesis of PH remains incompletely defined, and existing t...

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Detalles Bibliográficos
Autores principales: Wade, Brandy E., Zhao, Jingru, Ma, Jing, Hart, C. Michael, Sutliff, Roy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146334/
https://www.ncbi.nlm.nih.gov/pubmed/29927354
http://dx.doi.org/10.1177/2045894018788267