In silico sgRNA tool design for CRISPR control of quorum sensing in Acinetobacter species

CRISPR genome editing utilizes Cas9 nuclease and single guide RNA (sgRNA), which directs the nuclease to a specific site in the genome and makes a double-stranded break (DSB). Design of sgRNA for CRISPR-Cas targeting, and to promote CRISPR adaptation, uses a regulatory mechanism that ensures maximum...

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Detalles Bibliográficos
Autores principales: Karlapudi, Abraham Peele, T.C, Venkateswarulu, Tammineedi, Jahnavi, Srirama, Krupanidhi, Kanumuri, Lohit, Prabhakar Kodali, Vidya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146548/
https://www.ncbi.nlm.nih.gov/pubmed/30258941
http://dx.doi.org/10.1016/j.gendis.2018.03.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146548/
https://www.ncbi.nlm.nih.gov/pubmed/30258941
http://dx.doi.org/10.1016/j.gendis.2018.03.004

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