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Identification of a functional antioxidant response element at the HIF1A locus

Reactive oxygen species (ROS), which are a byproduct of oxidative metabolism, serve as signaling molecules in a number of physiological settings. However, if their levels are not tightly maintained, excess ROS lead to potentially cytotoxic oxidative stress. Accordingly, several transcriptional regul...

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Detalles Bibliográficos
Autores principales: Lacher, Sarah E., Levings, Daniel C., Freeman, Samuel, Slattery, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146589/
https://www.ncbi.nlm.nih.gov/pubmed/30241031
http://dx.doi.org/10.1016/j.redox.2018.08.014