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Identification of a functional antioxidant response element at the HIF1A locus
Reactive oxygen species (ROS), which are a byproduct of oxidative metabolism, serve as signaling molecules in a number of physiological settings. However, if their levels are not tightly maintained, excess ROS lead to potentially cytotoxic oxidative stress. Accordingly, several transcriptional regul...
Autores principales: | Lacher, Sarah E., Levings, Daniel C., Freeman, Samuel, Slattery, Matthew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146589/ https://www.ncbi.nlm.nih.gov/pubmed/30241031 http://dx.doi.org/10.1016/j.redox.2018.08.014 |
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