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RNAs as Proximity-Labeling Media for Identifying Nuclear Speckle Positions Relative to the Genome

It remains challenging to identify all parts of the nuclear genome that are in proximity to nuclear speckles, due to physical separation between the nuclear speckle cores and chromatin. We hypothesized that noncoding RNAs including small nuclear RNA (snRNAs) and Malat1, which accumulate at the perip...

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Detalles Bibliográficos
Autores principales: Chen, Weizhong, Yan, Zhangming, Li, Simin, Huang, Norman, Huang, Xuerui, Zhang, Jin, Zhong, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146591/
https://www.ncbi.nlm.nih.gov/pubmed/30240742
http://dx.doi.org/10.1016/j.isci.2018.06.005