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Identifying Involvement of H19-miR-675-3p-IGF1R and H19-miR-200a-PDCD4 in Treating Pulmonary Hypertension with Melatonin

Non-coding RNAs play an important role in the pathogenesis of pulmonary arterial hypertension (PAH). The aim of this study was to characterize the therapeutic role of melatonin as well as the underlying molecular mechanism (its effects on the expression of H19 and its downstream signaling pathways)...

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Detalles Bibliográficos
Autores principales: Wang, Ran, Zhou, Sijing, Wu, Peipei, Li, Min, Ding, Xing, Sun, Li, Xu, Xuan, Zhou, Xuexin, Zhou, Luqian, Cao, Chao, Fei, Guanghe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146608/
https://www.ncbi.nlm.nih.gov/pubmed/30240970
http://dx.doi.org/10.1016/j.omtn.2018.08.015