Cargando…

The S2 Subunit of Infectious Bronchitis Virus Beaudette Is a Determinant of Cellular Tropism

The spike (S) glycoprotein of the avian gammacoronavirus infectious bronchitis virus (IBV) is comprised of two subunits (S1 and S2), has a role in virulence in vivo, and is responsible for cellular tropism in vitro. We have previously demonstrated that replacement of the S glycoprotein ectodomain fr...

Descripción completa

Detalles Bibliográficos
Autores principales: Bickerton, Erica, Maier, Helena J., Stevenson-Leggett, Phoebe, Armesto, Maria, Britton, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146808/
https://www.ncbi.nlm.nih.gov/pubmed/30021894
http://dx.doi.org/10.1128/JVI.01044-18