The N Termini of TAR DNA-Binding Protein 43 (TDP43) C-Terminal Fragments Influence Degradation, Aggregation Propensity, and Morphology

Fragments of the TAR DNA-binding protein 43 (TDP43) are major components of intracellular aggregates associated with amyotrophic lateral sclerosis and frontotemporal dementia. A variety of C-terminal fragments (CTFs) exist, with distinct N termini; however, little is known regarding their difference...

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Detalles Bibliográficos
Autores principales: Kasu, Yasar Arfat T., Alemu, Samrawit, Lamari, Angela, Loew, Nicole, Brower, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146831/
https://www.ncbi.nlm.nih.gov/pubmed/29987190
http://dx.doi.org/10.1128/MCB.00243-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146831/
https://www.ncbi.nlm.nih.gov/pubmed/29987190
http://dx.doi.org/10.1128/MCB.00243-18

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