Cargando…

Asymmetric Synthesis of (R)‐1‐Alkyl‐Substituted Tetrahydro‐ß‐carbolines Catalyzed by Strictosidine Synthases

Stereoselective methods for the synthesis of tetrahydro‐ß‐carbolines are of significant interest due to the broad spectrum of biological activity of the target molecules. In the plant kingdom, strictosidine synthases catalyze the C−C coupling through a Pictet–Spengler reaction of tryptamine and seco...

Descripción completa

Detalles Bibliográficos
Autores principales: Pressnitz, Desiree, Fischereder, Eva‐Maria, Pletz, Jakob, Kofler, Christina, Hammerer, Lucas, Hiebler, Katharina, Lechner, Horst, Richter, Nina, Eger, Elisabeth, Kroutil, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146909/
https://www.ncbi.nlm.nih.gov/pubmed/29852524
http://dx.doi.org/10.1002/anie.201803372