Catalytic Modification of Dehydroalanine in Peptides and Proteins by Palladium‐Mediated Cross‐Coupling

Dehydroalanine (Dha) is a remarkably versatile non‐canonical amino acid often found in antimicrobial peptides. Herein, we present the catalytic modification of Dha by a palladium‐mediated cross‐coupling reaction. By using Pd(EDTA)(OAc)(2) as water‐soluble catalyst, a variety of arylboronic acids was...

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Detalles Bibliográficos
Autores principales: de Bruijn, A. Dowine, Roelfes, Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146911/
https://www.ncbi.nlm.nih.gov/pubmed/29923249
http://dx.doi.org/10.1002/chem.201802846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146911/
https://www.ncbi.nlm.nih.gov/pubmed/29923249
http://dx.doi.org/10.1002/chem.201802846

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