The role of miRNAs 34a, 146a, 320a and 542 in the synergistic anticancer effects of methyl 2-(5-fluoro-2-hydroxyphenyl)-1H- benzo[d]imidazole-5-carboxylate (MBIC) with doxorubicin in breast cancer cells

Combination Index (CI) analysis suggested that MBIC and doxorubicin synergistically inhibited up to 97% of cell proliferation in ER(+)/PR(+)MCF-7 and triple negative MDA-MB-231 breast cancer cell lines. Moreover, treatment of the breast cancer cells with the combined drugs resulted in lower IC(50) v...

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Detalles Bibliográficos
Autores principales: Hasanpourghadi, Mohadeseh, Abdul Majid, Nazia, Rais Mustafa, Mohd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147144/
https://www.ncbi.nlm.nih.gov/pubmed/30245930
http://dx.doi.org/10.7717/peerj.5577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147144/
https://www.ncbi.nlm.nih.gov/pubmed/30245930
http://dx.doi.org/10.7717/peerj.5577

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