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Polymorphism of the endothelin-1 gene (rs5370) is a potential contributor to sickle cell disease pathophysiology

Sickle cell disease has been shown to demonstrate extensive variability in disease severity among and between individuals, the variability highlighted by differing genetic haplotypes. Despite the abundance of reports of functional significance due to polymorphisms of endothelial nitric oxide synthas...

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Detalles Bibliográficos
Autores principales: Navarro, Kristen G., Agyingi, Smith E., Nwabuobi, Chinedu K., Thomas, Bolaji N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147159/
https://www.ncbi.nlm.nih.gov/pubmed/30258900
http://dx.doi.org/10.1016/j.gendis.2016.09.002