Current understanding and dispute on the function of the Wnt signaling pathway effector TCF7L2 in hepatic gluconeogenesis

Approximately 10 years ago, the Wnt signaling pathway effector TCF7L2 (=TCF-4) was recognized as a type 2 diabetes (T2D) risk gene through a genome wide association study (GWAS). As the correlation between TCF7L2 polymorphisms and T2D susceptibility has been reproducibly observed by numerous follow-...

Descripción completa

Detalles Bibliográficos
Autor principal: Jin, Tianru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147171/
https://www.ncbi.nlm.nih.gov/pubmed/30258876
http://dx.doi.org/10.1016/j.gendis.2015.10.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147171/
https://www.ncbi.nlm.nih.gov/pubmed/30258876
http://dx.doi.org/10.1016/j.gendis.2015.10.002

Ejemplares similares