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Puromycin aminonucleoside triggers apoptosis in podocytes by inducing endoplasmic reticulum stress

BACKGROUND: Puromycin aminonucleoside (PAN) is a known podocytotoxin. PAN-induced nephrosis is a widely used animal model for studying human idiopathic nephrotic syndrome. Abnormal protein accumulation associated with podocyte-specific endoplasmic reticulum (ER) stress damages cells structurally and...

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Detalles Bibliográficos
Autores principales: Min, Seo-Yoon, Ha, Dong-Soo, Ha, Tae-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Nephrology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147198/
https://www.ncbi.nlm.nih.gov/pubmed/30254845
http://dx.doi.org/10.23876/j.krcp.2018.37.3.210