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Zoledronate inhibits fibroblasts’ proliferation and activation via targeting TGF-β signaling pathway

BACKGROUND: Previous preclinical and clinical studies have demonstrated that zoledronate might inhibit neointimal hyperplasia at least partly by inhibiting the proliferation, adhesion and migration of vascular smooth muscle cells (VSMCs). However, whether zoledronate influences fibroblasts’ prolifer...

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Detalles Bibliográficos
Autores principales: Zhao, Zichang, Shen, Wei, Zhu, Hanbin, Lin, Lin, Jiang, Gening, Zhu, Yongzhe, Song, Hongyuan, Wu, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147205/
https://www.ncbi.nlm.nih.gov/pubmed/30271117
http://dx.doi.org/10.2147/DDDT.S168897