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Osteogenic differentiation enhances the MC3T3-E1 secretion of glycosaminoglycans with an affinity for basic fibroblast growth factor and bone morphogenetic protein-2

INTRODUCTION: It is generally recognized that a wide variety of morphogens and growth factors bind to the glycosaminoglycans (GAG) of proteoglycans (PG) to affect their bioavailability to ligands. Many growth factors involving in osteogenic differentiation require the GAG side chains to facilitate t...

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Detalles Bibliográficos
Autores principales: Fukunishi, Yoshiaki, Tabata, Yasuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147208/
https://www.ncbi.nlm.nih.gov/pubmed/30271866
http://dx.doi.org/10.1016/j.reth.2018.02.001