Reinterpretation of the localization of the ATP binding cassette transporter ABCG1 in insulin-secreting cells and insights regarding its trafficking and function

The ABC transporter ABCG1 contributes to the regulation of cholesterol efflux from cells and to the distribution of cholesterol within cells. We showed previously that ABCG1 deficiency inhibits insulin secretion by pancreatic beta cells and, based on its immunolocalization to insulin granules, propo...

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Detalles Bibliográficos
Autores principales: Harris, Megan T., Hussain, Syed Saad, Inouye, Candice M., Castle, Anna M., Castle, J. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147399/
https://www.ncbi.nlm.nih.gov/pubmed/30235209
http://dx.doi.org/10.1371/journal.pone.0198383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147399/
https://www.ncbi.nlm.nih.gov/pubmed/30235209
http://dx.doi.org/10.1371/journal.pone.0198383

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