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The activated DNA double-strand break repair pathway in cumulus cells from aging patients may be used as a convincing predictor of poor outcomes after in vitro fertilization-embryo transfer treatment

Women with advanced maternal age exhibit low anti-Müllerian hormone (AMH) levels and an altered follicular environment, which is associated with poor oocyte quality and embryonic developmental potential. However, the underlying mechanism is poorly understood. The present study aimed to assesswhether...

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Detalles Bibliográficos
Autores principales: Sun, Xu-lei, Jiang, Hao, Han, Dong-xu, Fu, Yao, Liu, Jian-bo, Gao, Yan, Hu, Shu-min, Yuan, Bao, Zhang, Jia-bao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147527/
https://www.ncbi.nlm.nih.gov/pubmed/30235328
http://dx.doi.org/10.1371/journal.pone.0204524