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Pechmann Reaction Promoted by Boron Trifluoride Dihydrate

The Pechmann reaction of substituted phenols 1a-e with methyl acetoacetate (2) can be activated by boron trifluoride dihydrate (3) to give the corresponding 4-methylcoumarin derivatives 4a-e in excellent yield (98-99 %).

Detalles Bibliográficos
Autores principales: Stoyanov, Edmont V., Mezger, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147532/
https://www.ncbi.nlm.nih.gov/pubmed/18007344
http://dx.doi.org/10.3390/10070762