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Pechmann Reaction Promoted by Boron Trifluoride Dihydrate
The Pechmann reaction of substituted phenols 1a-e with methyl acetoacetate (2) can be activated by boron trifluoride dihydrate (3) to give the corresponding 4-methylcoumarin derivatives 4a-e in excellent yield (98-99 %).
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147532/ https://www.ncbi.nlm.nih.gov/pubmed/18007344 http://dx.doi.org/10.3390/10070762 |