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Asymmetric Synthesis of Double Bond Isomers of the Structure Proposed for Pyrinodemin A and Indication of Its Structural Revision

Asymmetric synthesis of double bond isomers (+)-2 (Δ(15’,16’)) and (+)-3 (Δ(14’,15’)) of the structure (1) (Δ(16’,17’)) proposed for pyrinodemin A, a cytotoxic bis-pyridine alkaloid with a unique cis-cyclopent[c]isoxazolidine moiety from a marine sponge, has been accomplished. Pyrinodemin A was indi...

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Detalles Bibliográficos
Autores principales: Ishiyama, Haruaki, Tsuda, Masashi, Endo, Tadashi, Kobayashi, Jun’ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147537/
https://www.ncbi.nlm.nih.gov/pubmed/18007301
http://dx.doi.org/10.3390/10010312