Progranulin Deficient Mice Develop Nephrogenic Diabetes Insipidus

Loss-of-function mutations of progranulin are associated with frontotemporal dementia in humans, and its deficiency in mice is a model for this disease but with normal life expectancy and mild cognitive decline on aging. The present study shows that aging progranulin deficient mice develop progressi...

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Detalles Bibliográficos
Autores principales: Hardt, Stefanie, Valek, Lucie, Zeng-Brouwers, Jinyang, Wilken-Schmitz, Annett, Schaefer, Liliana, Tegeder, Irmgard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2018
Materias:
Orginal Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147595/
https://www.ncbi.nlm.nih.gov/pubmed/30271659
http://dx.doi.org/10.14336/AD.2017.1127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147595/
https://www.ncbi.nlm.nih.gov/pubmed/30271659
http://dx.doi.org/10.14336/AD.2017.1127

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