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Synthesis of New Potentially Bioactive Bicyclic 2-Pyridones

Three convenient methods of reduction of the nitro group of 5-nitroimidazoles and 5-nitrothiazole that bear a diethylmethylene malonate group in an ortho-like position with respect to the nitro group and cyclization of the resulting amino derivatives are reported. These reactions afforded the target...

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Detalles Bibliográficos
Autores principales: Crozet, Maxime D., George, Pascal, Crozet, Michel P., Vanelle, Patrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147647/
https://www.ncbi.nlm.nih.gov/pubmed/18007525
http://dx.doi.org/10.3390/10101318