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Microwave-Assisted Amination of a Chloropurine Derivative in the Synthesis of Acyclic Nucleoside Analogues
An efficient protocol for the amination of 6-chloropurine derivatives through nucleophilic aromatic substitution under microwave irradiation was developed and applied to the synthesis in two steps of a series of new acyclic nucleosides (acyclovir analogues) starting from commercially available compo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147686/ https://www.ncbi.nlm.nih.gov/pubmed/18007322 http://dx.doi.org/10.3390/10020508 |