Improved Synthesis of β-D-6-Methylpurine Riboside and Antitumor Effects of the β-D- and α-D-Anomers

6-Methylpurine-β-D-riboside (β-D-MPR) has been synthesized by coupling 6-methylpurine and 1-O-acetyl-2,3,5-tri-O-benzoyl-D-ribose using conditions that produce the β-D-anomer exclusively. The in vitro antitumor effects of β-D-MPR and 6-methyl-purine-α-D-riboside (α-D-MPR) in five human tumor cell li...

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Detalles Bibliográficos
Autores principales: Marasco, Canio J., Pera, Paula J., Spiess, Arthur J., Bernacki, Ralph, Sufrin, Janice R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147709/
https://www.ncbi.nlm.nih.gov/pubmed/18007371
http://dx.doi.org/10.3390/10081015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147709/
https://www.ncbi.nlm.nih.gov/pubmed/18007371
http://dx.doi.org/10.3390/10081015

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