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Promoted Angiogenesis and Osteogenesis by Dexamethasone-loaded Calcium Phosphate Nanoparticles/Collagen Composite Scaffolds with Microgroove Networks

Reconstruction of large bone defects remains a clinical challenge because current approaches involving surgery and bone grafting often do not yield satisfactory outcomes. For artificial bone substitutes, angiogenesis plays a pivotal role to achieve the final success of newly regenerated bone. In thi...

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Detalles Bibliográficos
Autores principales: Chen, Ying, Chen, Shangwu, Kawazoe, Naoki, Chen, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147787/
https://www.ncbi.nlm.nih.gov/pubmed/30237563
http://dx.doi.org/10.1038/s41598-018-32495-y