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CCN6-mediated MMP-9 activation enhances metastatic potential of human chondrosarcoma

Chondrosarcomas are primary malignant bone tumors that have a poor prognosis. WNT1-inducible signaling pathway protein-3 (WISP-3, also termed CCN6) belongs to the CCN family of proteins and is implicated in the regulation of various cellular functions, such as cell proliferation, differentiation, an...

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Detalles Bibliográficos
Autores principales: Tzeng, Huey-En, Tang, Chih-Hsin, Wu, Sz-Hua, Chen, Hsien-Te, Fong, Yi-Chin, Lu, Yung-Chang, Chen, Wei-Cheng, Huang, Hsien-Da, Lin, Chih-Yang, Wang, Shih-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147788/
https://www.ncbi.nlm.nih.gov/pubmed/30237403
http://dx.doi.org/10.1038/s41419-018-1008-9