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CRISPR-Cas immunity, DNA repair and genome stability

Co-opting of CRISPR-Cas ‘Interference’ reactions for editing the genomes of eukaryotic and prokaryotic cells has highlighted crucial support roles for DNA repair systems that strive to maintain genome stability. As front-runners in genome editing that targets DNA, the class 2 CRISPR-Cas enzymes Cas9...

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Detalles Bibliográficos
Autores principales: Cubbon, Andrew, Ivancic-Bace, Ivana, Bolt, Edward L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147917/
https://www.ncbi.nlm.nih.gov/pubmed/30209206
http://dx.doi.org/10.1042/BSR20180457