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HP1 cooperates with CAF-1 to compact heterochromatic transgene repeats in mammalian cells

The nuclear organization of tightly condensed heterochromatin plays important roles in regulating gene transcription and genome integrity. Heterochromatic domains are usually present at chromosomal regions containing a large array of repeated DNA sequences. We previously showed that integration of a...

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Detalles Bibliográficos
Autores principales: Yan, Haiyan, Xiang, Xingfeng, Chen, Qinfu, Pan, Xuan, Cheng, Hankun, Wang, Fangwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147918/
https://www.ncbi.nlm.nih.gov/pubmed/30237539
http://dx.doi.org/10.1038/s41598-018-32381-7