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HP1 cooperates with CAF-1 to compact heterochromatic transgene repeats in mammalian cells
The nuclear organization of tightly condensed heterochromatin plays important roles in regulating gene transcription and genome integrity. Heterochromatic domains are usually present at chromosomal regions containing a large array of repeated DNA sequences. We previously showed that integration of a...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147918/ https://www.ncbi.nlm.nih.gov/pubmed/30237539 http://dx.doi.org/10.1038/s41598-018-32381-7 |