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Vascularization converts the lineage fate of bone mesenchymal stem cells to endothelial cells in tissue-engineered bone grafts by modulating FGF2-RhoA/ROCK signaling

The prevascularization of tissue-engineered bone grafts (TEBGs) has been shown to accelerate capillary vessel ingrowth in bone defect remodeling and to enhance new bone formation. However, the exact mechanisms behind this positive effect remain unknown. Here, we report that basic fibroblast growth f...

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Detalles Bibliográficos
Autores principales: Li, Donglin, Cheng, Pengzhen, Jiang, Huijie, Cao, Tianqing, Wang, Jimeng, Gao, Yi, Lin, Yangjing, Wang, Chunmei, Zhang, Shuaishuai, Li, Junqin, Liu, Bin, Song, Yue, Yang, Liu, Pei, Guoxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147920/
https://www.ncbi.nlm.nih.gov/pubmed/30237398
http://dx.doi.org/10.1038/s41419-018-0999-6