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Vascularization converts the lineage fate of bone mesenchymal stem cells to endothelial cells in tissue-engineered bone grafts by modulating FGF2-RhoA/ROCK signaling
The prevascularization of tissue-engineered bone grafts (TEBGs) has been shown to accelerate capillary vessel ingrowth in bone defect remodeling and to enhance new bone formation. However, the exact mechanisms behind this positive effect remain unknown. Here, we report that basic fibroblast growth f...
Autores principales: | Li, Donglin, Cheng, Pengzhen, Jiang, Huijie, Cao, Tianqing, Wang, Jimeng, Gao, Yi, Lin, Yangjing, Wang, Chunmei, Zhang, Shuaishuai, Li, Junqin, Liu, Bin, Song, Yue, Yang, Liu, Pei, Guoxian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147920/ https://www.ncbi.nlm.nih.gov/pubmed/30237398 http://dx.doi.org/10.1038/s41419-018-0999-6 |
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