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Acylated-acyl carrier protein stabilizes the Pseudomonas aeruginosa WaaP lipopolysaccharide heptose kinase

Phosphorylation of Pseudomonas aeruginosa lipopolysaccharide (LPS) is important for maintaining outer membrane integrity and intrinsic antibiotic resistance. We solved the crystal structure of the LPS heptose kinase WaaP, which is essential for growth of P. aeruginosa. WaaP was structurally similar...

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Detalles Bibliográficos
Autores principales: Kreamer, Naomi N. K., Chopra, Rajiv, Caughlan, Ruth E., Fabbro, Doriano, Fang, Eric, Gee, Patricia, Hunt, Ian, Li, Min, Leon, Barbara C., Muller, Lionel, Vash, Brian, Woods, Angela L., Stams, Travis, Dean, Charles R., Uehara, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147952/
https://www.ncbi.nlm.nih.gov/pubmed/30237436
http://dx.doi.org/10.1038/s41598-018-32379-1