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Aberrant activation of Notch-1 signaling inhibits podocyte restoration after islet transplantation in a rat model of diabetic nephropathy

Signaling abnormalities play important roles during podocyte injury and have been indicated as crucial events for triggering many glomerular diseases. There is emerging evidence demonstrating significant improvements in preventing renal injury and restoring podocytes after islet transplantation. How...

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Detalles Bibliográficos
Autores principales: He, Yunqiang, Zhang, Mei, Wu, Ying, Jiang, Hemin, Fu, Hongxing, Cai, Yong, Xu, Ziqiang, Liu, Chengyang, Chen, Bicheng, Yang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148077/
https://www.ncbi.nlm.nih.gov/pubmed/30237561
http://dx.doi.org/10.1038/s41419-018-0985-z