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When designing vaccines, consider the starting material: the human B cell repertoire
Most viral vaccines provide protection from infection through the generation of neutralizing antibodies (nAbs). The repertoire of B cells responding to immunization is the starting material from which nAbs eventually arise. Immunization strategies are increasingly targeting precise B cell specificit...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148213/ https://www.ncbi.nlm.nih.gov/pubmed/30190230 http://dx.doi.org/10.1016/j.coi.2018.08.002 |