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When designing vaccines, consider the starting material: the human B cell repertoire

Most viral vaccines provide protection from infection through the generation of neutralizing antibodies (nAbs). The repertoire of B cells responding to immunization is the starting material from which nAbs eventually arise. Immunization strategies are increasingly targeting precise B cell specificit...

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Detalles Bibliográficos
Autores principales: Havenar-Daughton, Colin, Abbott, Robert K., Schief, William R., Crotty, Shane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148213/
https://www.ncbi.nlm.nih.gov/pubmed/30190230
http://dx.doi.org/10.1016/j.coi.2018.08.002