Anti-inflammatory action of cysteine derivative S-1-propenylcysteine by inducing MyD88 degradation

The degradation of target proteins by small molecules utilizing the cellular proteolytic system is featured as a treatment strategy of several diseases. We found that S-1-propenylcysteine (S1PC) among several cysteine derivatives in aged garlic extract inhibited TLR-mediated IL-6 production by induc...

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Detalles Bibliográficos
Autores principales: Suzuki, Jun-ichiro, Kodera, Yukihiro, Miki, Satomi, Ushijima, Mitsuyasu, Takashima, Miyuki, Matsutomo, Toshiaki, Morihara, Naoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148218/
https://www.ncbi.nlm.nih.gov/pubmed/30237533
http://dx.doi.org/10.1038/s41598-018-32431-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148218/
https://www.ncbi.nlm.nih.gov/pubmed/30237533
http://dx.doi.org/10.1038/s41598-018-32431-0

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