Protease-activated receptor 2 signaling modulates susceptibility of colonic epithelium to injury through stabilization of YAP in vivo

Hippo signaling plays critical roles in intestinal regeneration. However, the mechanisms which regulate its activity in vivo are largely unknown. We hypothesize that protease-activated receptor 2 (PAR2) signaling, which could be activated by trypsin, might affect YAP activity in the setting of tissu...

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Detalles Bibliográficos
Autores principales: He, Longmei, Ma, Yiming, Li, Weiwei, Han, Wenxiao, Zhao, Xinhua, Wang, Hongying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148223/
https://www.ncbi.nlm.nih.gov/pubmed/30237580
http://dx.doi.org/10.1038/s41419-018-0995-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148223/
https://www.ncbi.nlm.nih.gov/pubmed/30237580
http://dx.doi.org/10.1038/s41419-018-0995-x

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