RIF1 promotes tumor growth and cancer stem cell-like traits in NSCLC by protein phosphatase 1-mediated activation of Wnt/β-catenin signaling

Wnt/β-catenin signaling is essential for proliferation and maintenance of cancer stem cell-like traits of various cancer cells. In non-small-cell lung carcinoma (NSCLC), the mechanisms underlying the hyperactivation of Wnt signaling remain unclear, as mutations in APC and β-catenin genes are rare in...

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Detalles Bibliográficos
Autores principales: Mei, Ying, Liu, Yong-Bin, Cao, Shan, Tian, Zheng-Wen, Zhou, Hong-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148239/
https://www.ncbi.nlm.nih.gov/pubmed/30237512
http://dx.doi.org/10.1038/s41419-018-0972-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148239/
https://www.ncbi.nlm.nih.gov/pubmed/30237512
http://dx.doi.org/10.1038/s41419-018-0972-4

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