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C-Abl is not actıvated in DNA damage-induced and Tap63-mediated oocyte apoptosıs in human ovary
There is a controversy in literature as to whether c-Abl is crucial for the induction of TAp63-mediated apoptosis and whether that inhibition of c-Abl with imatinib, which was designed to inhibit the oncogenic kinase BCR-ABL and c-kit, protects oocytes from chemotherapy-induced apoptosis in mice. No...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148240/ https://www.ncbi.nlm.nih.gov/pubmed/30237472 http://dx.doi.org/10.1038/s41419-018-1026-7 |