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A novel mechanism of plasminogen activation in epithelial and mesenchymal cells

Cancer dissemination is initiated by the movement of cells into the vasculature which has been reported to be triggered by EMT (epithelial to mesenchymal transition). Cellular dissemination also requires proteases that remodel the extracellular matrix. The protease, plasmin is a prominent player in...

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Detalles Bibliográficos
Autores principales: Bydoun, Moamen, Sterea, Andra, Weaver, Ian C. G., Bharadwaj, Alamelu G., Waisman, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148250/
https://www.ncbi.nlm.nih.gov/pubmed/30237490
http://dx.doi.org/10.1038/s41598-018-32433-y