The FAK inhibitor BI 853520 exerts anti-tumor effects in breast cancer

Focal adhesion kinase (FAK) is a cytoplasmic tyrosine kinase that regulates a plethora of downstream signaling pathways essential for cell migration, proliferation and death, processes that are exploited by cancer cells during malignant progression. These well-established tumorigenic activities, tog...

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Detalles Bibliográficos
Autores principales: Tiede, Stefanie, Meyer-Schaller, Nathalie, Kalathur, Ravi Kiran Reddy, Ivanek, Robert, Fagiani, Ernesta, Schmassmann, Philip, Stillhard, Patrick, Häfliger, Simon, Kraut, Norbert, Schweifer, Norbert, Waizenegger, Irene C., Bill, Ruben, Christofori, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148276/
https://www.ncbi.nlm.nih.gov/pubmed/30237500
http://dx.doi.org/10.1038/s41389-018-0083-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148276/
https://www.ncbi.nlm.nih.gov/pubmed/30237500
http://dx.doi.org/10.1038/s41389-018-0083-1

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