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Proinsulin-mediated induction of type 1 diabetes in HLA-DR4-transgenic mice
Antigen-specific immunotherapy of autoimmune disease currently remains the only potentially curative approach. However, translation of promising pre-clinical results into successful clinical application has proven challenging. In part, this is because pre-clinical findings in mouse models have to be...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148278/ https://www.ncbi.nlm.nih.gov/pubmed/30237494 http://dx.doi.org/10.1038/s41598-018-32546-4 |