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Proinsulin-mediated induction of type 1 diabetes in HLA-DR4-transgenic mice

Antigen-specific immunotherapy of autoimmune disease currently remains the only potentially curative approach. However, translation of promising pre-clinical results into successful clinical application has proven challenging. In part, this is because pre-clinical findings in mouse models have to be...

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Detalles Bibliográficos
Autores principales:	Verhagen, Johan, Smith, Emma L., Whettlock, Emily M., Macintyre, Benedict, Peakman, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148278/ https://www.ncbi.nlm.nih.gov/pubmed/30237494 http://dx.doi.org/10.1038/s41598-018-32546-4

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