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Pharmacological Characterization of Dezocine, a Potent Analgesic Acting as a κ Partial Agonist and μ Partial Agonist

Dezocine is becoming dominated in China market for relieving moderate to severe pain. It is believed that Dezocine’s clinical efficacy and little chance to provoke adverse events during the therapeutic process are mainly attributed to its partial agonist activity at the μ opioid receptor. In the pre...

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Detalles Bibliográficos
Autores principales: Wang, Yu-Hua, Chai, Jing-Rui, Xu, Xue-Jun, Ye, Ru-Feng, Zan, Gui-Ying, Liu, George Yun-Kun, Long, Jian-Dong, Ma, Yan, Huang, Xiang, Xiao, Zhi-Chao, Dong, Hu, Wang, Yu-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148296/
https://www.ncbi.nlm.nih.gov/pubmed/30237513
http://dx.doi.org/10.1038/s41598-018-32568-y