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Pharmacological Characterization of Dezocine, a Potent Analgesic Acting as a κ Partial Agonist and μ Partial Agonist
Dezocine is becoming dominated in China market for relieving moderate to severe pain. It is believed that Dezocine’s clinical efficacy and little chance to provoke adverse events during the therapeutic process are mainly attributed to its partial agonist activity at the μ opioid receptor. In the pre...
Autores principales: | Wang, Yu-Hua, Chai, Jing-Rui, Xu, Xue-Jun, Ye, Ru-Feng, Zan, Gui-Ying, Liu, George Yun-Kun, Long, Jian-Dong, Ma, Yan, Huang, Xiang, Xiao, Zhi-Chao, Dong, Hu, Wang, Yu-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148296/ https://www.ncbi.nlm.nih.gov/pubmed/30237513 http://dx.doi.org/10.1038/s41598-018-32568-y |
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