Critical assessment of approaches for molecular docking to elucidate associations of HLA alleles with adverse drug reactions

Adverse drug reactions have been linked with genetic polymorphisms in HLA genes in numerous different studies. HLA proteins have an essential role in the presentation of self and non-self peptides, as part of the adaptive immune response. Amongst the associated drugs-allele combinations, anti-HIV dr...

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Detalles Bibliográficos
Autores principales: Ramsbottom, Kerry A., Carr, Daniel F., Jones, Andrew R., Rigden, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148408/
https://www.ncbi.nlm.nih.gov/pubmed/30125869
http://dx.doi.org/10.1016/j.molimm.2018.08.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148408/
https://www.ncbi.nlm.nih.gov/pubmed/30125869
http://dx.doi.org/10.1016/j.molimm.2018.08.003

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