G-Quadruplex Identification in the Genome of Protozoan Parasites Points to Naphthalene Diimide Ligands as New Antiparasitic Agents

[Image: see text] G-quadruplexes (G4) are DNA secondary structures that take part in the regulation of gene expression. Putative G4 forming sequences (PQS) have been reported in mammals, yeast, bacteria, and viruses. Here, we present PQS searches on the genomes of T. brucei, L. major, and P. falcipa...

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Detalles Bibliográficos
Autores principales: Belmonte-Reche, Efres, Martínez-García, Marta, Guédin, Aurore, Zuffo, Michela, Arévalo-Ruiz, Matilde, Doria, Filippo, Campos-Salinas, Jenny, Maynadier, Marjorie, López-Rubio, José Juan, Freccero, Mauro, Mergny, Jean-Louis, Pérez-Victoria, José María, Morales, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148440/
https://www.ncbi.nlm.nih.gov/pubmed/29323491
http://dx.doi.org/10.1021/acs.jmedchem.7b01672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148440/
https://www.ncbi.nlm.nih.gov/pubmed/29323491
http://dx.doi.org/10.1021/acs.jmedchem.7b01672

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