Custom made inclusion bodies: impact of classical process parameters and physiological parameters on inclusion body quality attributes

BACKGROUND: The bacterium E. coli is a major host for recombinant protein production of non-glycosylated products. Depending on the expression strategy, the recombinant protein can be located intracellularly. In many cases the formation of inclusion bodies (IBs), protein aggregates inside of the cyt...

Descripción completa

Detalles Bibliográficos
Autores principales: Slouka, Christoph, Kopp, Julian, Hutwimmer, Stefan, Strahammer, Michael, Strohmer, Daniel, Eitenberger, Elisabeth, Schwaighofer, Andreas, Herwig, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148765/
https://www.ncbi.nlm.nih.gov/pubmed/30236107
http://dx.doi.org/10.1186/s12934-018-0997-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148765/
https://www.ncbi.nlm.nih.gov/pubmed/30236107
http://dx.doi.org/10.1186/s12934-018-0997-5

Ejemplares similares